Scientifically speaking, a full frame camera allows more light in, hence a better quality picture. But after you throw in higher megapixels, better glass, and proper camera settings, good lighting, just about any camera gives you a good pic. I'm no expert mind you but they do have an advantage in low light situations. It has been my experience, the larger the sensor, the less grain. Again, throw in post production, noise reduction, active D lighting, etc, etc, the rules of the game change again. A great photographer can take a lousy picture and a lousy photographer can get lucky and take a great picture. Bottom line is, knowledge of principles of photography and your equipment make the difference in getting lousy or great pics!!!