I set mine to focus exclusively with the AF-On button, and once I got used to it, I'll never switch back. Want AF-C? Hold the button down and follow the subject. Want AF-S? Just press and release the button. Want to focus and recompose? Use single focus point, focus on the subject, release the button, recompose, and shoot. No need to press any other button to hold focus as you recompose. Since focus locks as soon as you release, you don't have the half shutter press trying to undo your intended focus. I can really see the advantage for fast moving action, as you can just set 51 pt matrix focusing, keep the button depressed the whole time you're following your subject, and shoot without hesitation. Set the camera to shutter priority in the menu so it will still shoot with the button depressed.
Then, in combination with the different AF detection points, you have everything in one single button.