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Message: <blockquote data-quote="STM" data-source="post: 735952" data-attributes="member: 12827"><p>There are any number of reasons. You can have subject or camera movement (which is a biggie if you are using a long lens), the AF choosing a different focus spot rather than the one you want, misalignment inside the lens itself, choosing a high ISO to get a high shutter speed, etc.  I suggest you use a tripod and a gimbal head for your shots using a long lens, especially a 600mm one. If not a tripod, at least a monopod.  My 600mm f/4 AIS Nikkor is my go-to lens for nature photography, but at 14 pounds (lens alone) and over 2 feet long, it is just not hand holdable, especially since it is manual focus. But put it on a sturdy tripod with a gimbal head and it is a dream to use!</p></blockquote><p></p>