What Dave said.
I shoot most of my macros at 1/200s or faster and even then quite many don't make it when checking them at 100%. Some look great as a full shot but once I look at them in detail, they fall apart.
The closer you get, the more any movement is magnified. Yours, the subject, wind... you name it. Depending what lens you use, you have to find a good balance between a fast shutter and enough depth. Your aperture is also rather wide for close-up. The closer, the less DOF -the more fuzziness- you'll have and you'll again have to find what works best for what shot.
Often it is better to step back and take a sharper shot with more depth which you'll crop some more, than having a "big" shot that you can no longer crop because of quality.