I've done the 45 degree angle thing and dot tune before. Dot tune didn't work on my 16-85, it definitely back focused constantly. For all primes it did work wonders however. I'll continue to use dot tune because it's A: easier, B: takes less time, C: accurate enough for what you need to shoot.
However, the less time you spend worrying about focus "issues", the more you can spend actually being a photographer.