The subject has a great expression but the photo has some missed opportunities. The first one is sitting out of sight to your left....a big soft source of light perfect for portraits. When setting up a shot, even if just 2 seconds thinking about the goal, ask yourself about the direction and quality of light. By turning your subject a bit more towards the window, it would have changed everything. Having deep shadows on the face, noise becomes a problem in the dark shadows where the eyes are. Portraits are about eyes. We humans, and all animals are eye seeking creatures and our brains are keyed into finding eyes even hidden in a confusing scene, we instantly spot eyes and whether they are focused on us. Most likely it was an evolutionary adaptation that allowed long enough survival to raise another generation, since knowing that lion is there by seeing its eyes in the mass of complex background of tall grasses or shrubs was a very good thing to know. We can spot people in a large stadium crowd who out of thousands, who are focused on you. We sense when eyes are focused on us with incredible reliability. Given that eyes are important, at least 1 eye needs to be in focus and sharp for us to perceive the entire image is sharp even when it isn't. In fact, if the eyes, at least the nearest one is sharp, the rest of the image can be intentionally unsharp but our brains will assume it is.
The impression of sharpness is related to light levels, the higher you have to raise ISO the less data there is above a noise threshold. With light comes color fidelity, dim light loses both detail and color information. So light, its quality, and direction are keys to any photograph and this photo suffers from loss of signal to noise ratio, color fidelity and detail of the eyes because she is facing the darkness instead of the window light.
Photographers often refer to light as being high quality or not. Light is light so what is meant? High quality is a term used to describe the relative apparent cross-section of the light source, to the subject. You window light is good quality of light not because the sun is bright...the sun is a poor quality of light by itself because while being very large, relative to the subject it is a tiny concentrated source a few millimeters across. The high-quality aspect of the sunlight through the window is the fact that the bright light is scattered by the glass, and reflections from all the surfaces hit by that direct light of the sun. The room lights up with a golden glow so the whole left side of the room becomes the light source. Take the same photo outdoors were that scattering is minimal, shadows become very hard, hard-edged and deep. Very unflattering for faces. The same scene on an overcast day and it becomes higher quality due to having the entire cloud layer being the light source, and shadows become soft and diffused.
Shooting a toddler is hard...they are like capturing a cyclone, so it is best to practice with adults or even a manikin such as a hair dresser's styrofoam head used to style wigs. They have fairly flat features which is perfect for learning about shadows and approach angle of the light.
In many cases, highly directional light such as from a cloudless sunny day is desirable but not on faces. We see the contours of a face by the shadows cast by facial features and if those shadows are hard-edged and very dark, it gives an appearance of a much older person, with hard angular features for an overall unflattering look. A light source that is broader relative to the subject, like the room full of scattered light or moving someone into the shade of a tree for a portrait will almost always look more flattering. A broader light source has the trait referred to "wrap" which is how the light source being larger in relation to a face size, the light tends to wrap around the sides of the face. Moving that source, without changing the light, closer, means it appears to be larger in relation to the subject, and moving that light further away shrinks the apparent cross-section of the light so it becomes more directional and shadows become harder.
In summary, the photo has a good expression but hides any detail of the eyes, creates a distraction of well-lit room features that do not add to the story. The low light in the shadows are not as noisy as with lesser cameras, the D500 is the best low light crop sensor camera made so noise is not as bad as with other bodies, but the noise still detracts from the image by hiding details that do contribute to the story. Shadows are not bad, they are as important as light, both are needed in a photo but shadows that hide information essential to a story is not helping.
Good luck and have fun learning about the never-ending path of photography knowledge. Cameras are simple to master, photography is not.
. Photography is ART. And being artistic is no easy task.