Here is an image I took last month with my Z8 and 180-600. It was taken handheld. The first image is the full frame, for reference.
The second is a heavier crop than I would ever do under normal conditions. You be the judge if the resolution is still there. The TIF file for the full sized is 130 MB (8256x5504), and the cropped is 5.6 MB(1133x1699). When viewing the TIF file on my monitor, vs this lower resolution JPG, I notice more detail and contrast in the TIF than this compressed, slighter smaller file for posting. I could probably edit this and add a little more contrast, texture and sharpness to bring it in line with the TIF file. Again, this is an extreme crop. It is far more than to the equivalent of a crop frame image at this focal length, and much more than most folks would ever normally crop, even with the higher resolution sensor. Full disclosure, this was shot under good conditions for resolution ( full late morning sun, 1/3000 sec with ISO 400 @F/6.3). A lower ISO and stopping down one stop or so would probably increase resolution a little bit.
For clarification, I do not use a shorter lens and then crop to get more reach, if a longer lens is available. I try and get the image as close to ideal in the camera (leaving a little extra for fine tuning in post), but often am further from my subject than I would like. This picture was taken at distance, and was as close as I could get with the longest lens I own. This is frequently an issue for wildlife photography, and we frequently wish for longer lenses, but have to use the lens we have in order to get the shot.
As to the concerns about depth of field, my understanding is that the depth of field is the same for a given focal length regardless of the sensor size. Critical focus may be an issue.
My experience has been going from a 24MP crop frame to a 24MP full frame to 46MP full frame. The 46MP images allow for far more cropping when cropping is needed. If something happened to my Z8, and all I could afford was a crop frame body, I would gladly go out and take pictures with it. I see tons of truly excellent images taken with crop frame cameras. I would, however, greatly miss the flexibility of the higher resolution images.