You don't mention if you are shooting in af-s or af-c. You can set the priority mode for each.
This is really important. You need to set these settings for
every mode
IF you
always want to shoot in either af-s or af-c. Otherwise, when you change modes, you might revert to the default settings which might be af-s with focus priority. For example, you might start out in Manual Mode with AF-C with release priority but later decide to switch to Shutter Priority. It's possible Shutter Priority might be set to AF-S with focus priority, and that can cause a hiccup if trying to shoot quickly.
Just be aware changing the setting in one mode doesn't affect the others.
I make use of U1 and U2. Those you can choose to set however you want. My U2 is set for BBF in Manual Mode with Auto ISO. My ISO is capped around 6400.
If you cap your ISO too low, your camera won't be able to expose properly (especially overexpose) in certain situations depending on your settings.
My aperture is set for f/8 and the shutter set for 1/1000", AF-C with release priority. I don't remember offhand how many focus points I have enabled, but those are saved as well.
When I switch to U2 from a different mode, all these settings are stored in the camera and are accessible immediately.