I have used F-mount lenses on a Z7, then a Z7 II, without any optical, mechanical or electric/electronic problem. I did because for some time, there were no Z-mount equivalents on the market. In fact, I still do use my three F-mount tilt-shifts, as Nikon hasn’t seen fit to offer such lenses in the new mount.
Of course, the optical quality is not the same, I see this now that I’m using Z-mounts (and I used to use top-notch F-mounts), but if you’re used to the IQ of your F-mounts, and happy with it, you will find it again using a mirrorless camera.
The tilt-shifts are a breed of their own, of course. For reasons linked to their shifting capabilities, they had to be optically designed for an image circle much larger than the 24 × 36 mm sensor, and of course they retain their exceptional optical qualities on a mirrorless’ sensor. As a downside, their performance is mediocre in terms of chromatic aberrations and resistance to flare, especially the older ones (45 and 85mm).